Patients with end stage renal disease suffer from a multitude of haemostatic disorders. This bleeding is mainly due to impaired platelet function present in the uremic patients. Both the platelets adhesion (platelet vessel wall interaction) and the aggregation are affected resulting in bleeding diathesis. Studies have shown that haemodialysis of these patients in time results in the decreased hemorrhagic episodes.

Impact-R is can be utilized in these cases for the early detection of platelet function abnormalities, and can help in reducing the morbidity and mortality associated with hemorrhage in end stage renal disease.