{"id":227,"date":"2011-12-25T16:41:44","date_gmt":"2011-12-25T16:41:44","guid":{"rendered":"https:\/\/impact-r.com\/?p=227"},"modified":"2012-01-07T13:06:12","modified_gmt":"2012-01-07T13:06:12","slug":"impact-r-as-screening-tool-for-bleeding-disorders-in-children","status":"publish","type":"post","link":"https:\/\/impact-r.com\/?p=227","title":{"rendered":"Impact-R as Screening Tool for Bleeding Disorders in Children"},"content":{"rendered":"<p>What is a screening test? It is a device used to detect disease or a precursor of a disease in persons who do not have signs and symptoms. The decision to screen should be based on a careful history and assessment of risk factors.<\/p>\n<p>Children with a family history of bleeding disorders may well benefit from a<\/p>\n<div id=\"attachment_269\" style=\"width: 210px\" class=\"wp-caption alignright\"><a href=\"https:\/\/impact-r.com\/wp-content\/uploads\/2011\/12\/Alexei_Nikolaevich1.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-269\" class=\"size-medium wp-image-269\" src=\"https:\/\/impact-r.com\/wp-content\/uploads\/2011\/12\/Alexei_Nikolaevich1-200x300.jpg\" alt=\"\" width=\"200\" height=\"300\" srcset=\"https:\/\/impact-r.com\/wp-content\/uploads\/2011\/12\/Alexei_Nikolaevich1-200x300.jpg 200w, https:\/\/impact-r.com\/wp-content\/uploads\/2011\/12\/Alexei_Nikolaevich1.jpg 220w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a><p id=\"caption-attachment-269\" class=\"wp-caption-text\">Alexei Nikolaevich, heir to the Russian throne, had Hemophilia B.<\/p><\/div>\n<p>screening test. The child\u2019s future health and quality of life will depend on the diagnosis of a serious medical condition ahead of the time when signs and symptoms manifest. Children with a family history of congenital platelet function defects, clotting factor deficiencies, and defects in primary or secondary aggregation are among those that will put a screening test to good use.<\/p>\n<p>A <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19799714\" target=\"_blank\">study by Revel-Vilk, et.al.<\/a> evaluated the use of the Impact-R as a one such screening test. They concluded that the <a href=\"https:\/\/impact-r.com\/impact-r-laboratory-platelet-function-cone-and-plate-analyser\/\" target=\"_blank\">Impact-R<\/a> is highly effective in excluding a bleeding disorder in patients with normal result. However, in case of abnormal Impact-R results, further testing is necessary to diagnose the condition.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is a screening test? It is a device used to detect disease or a precursor of a disease in persons who do not have signs and symptoms. The decision to screen should be based on a careful history and assessment of risk factors. Children with a family history of bleeding disorders may well benefit [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59],"tags":[107,108,132,149,133,50,106],"class_list":["post-227","post","type-post","status-publish","format-standard","hentry","category-disorders-use-of-impact-r-in-research","tag-bleeding-disorder","tag-congenital","tag-congenital-platelet-function-defects","tag-defects-in-primary-and-secondary-aggregation","tag-hemophilia-b","tag-platelet-function","tag-screening-test"],"_links":{"self":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts\/227","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=227"}],"version-history":[{"count":8,"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts\/227\/revisions"}],"predecessor-version":[{"id":241,"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts\/227\/revisions\/241"}],"wp:attachment":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=227"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=227"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=227"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}