{"id":317,"date":"2012-01-18T17:23:53","date_gmt":"2012-01-18T17:23:53","guid":{"rendered":"https:\/\/impact-r.com\/?p=317"},"modified":"2025-07-22T12:09:41","modified_gmt":"2025-07-22T12:09:41","slug":"impact-r-to-determine-effect-of-erythrocytosis-and-thrombocytosis","status":"publish","type":"post","link":"https:\/\/impact-r.com\/?p=317","title":{"rendered":"Impact-R to Determine Effect of Erythrocytosis and Thrombocytosis"},"content":{"rendered":"

Impact-R, a cone and platelet analyzer can be used to determine the effect of increased erythrocyte and thrombocyte counts on platelet adhesion and aggregation.<\/p>\n

In a study by Peerschke, et.al.<\/a>, the cone and platelet analyzer was used to determine platelet adhesion in terms of surface coverage (%SC) and platelet aggregation in terms of aggregate size (AS in um).<\/p>\n

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A blood clot on electron microscopy.<\/p><\/div>\n

The study noted that erythrocytosis increased aggregate size and thrombocytosis increased surface coverage. The specimen used was whole blood from healthy individuals with varying RBC and platelet counts.<\/p>\n

The study also investigated blood from individuals with myeloproliferative diseases. They noted that differences in the platelet function parameters were seen in MPD patients undergoing different therapies.<\/p>\n","protected":false},"excerpt":{"rendered":"

Impact-R, a cone and platelet analyzer can be used to determine the effect of increased erythrocyte and thrombocyte counts on platelet adhesion and aggregation. In a study by Peerschke, et.al., the cone and platelet analyzer was used to determine platelet adhesion in terms of surface coverage (%SC) and platelet aggregation in terms of aggregate size […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59],"tags":[169,166,168,83,82,167],"class_list":["post-317","post","type-post","status-publish","format-standard","hentry","category-disorders-use-of-impact-r-in-research","tag-cone-and-platelet-analyzer","tag-erythrocytosis","tag-myeloproliferative-disease","tag-platelet-adhesion","tag-platelet-aggregation","tag-thrombocytosis"],"_links":{"self":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts\/317","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=317"}],"version-history":[{"count":4,"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts\/317\/revisions"}],"predecessor-version":[{"id":387,"href":"https:\/\/impact-r.com\/index.php?rest_route=\/wp\/v2\/posts\/317\/revisions\/387"}],"wp:attachment":[{"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=317"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=317"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/impact-r.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=317"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}